Gallery Game: Smartphone-based assessment of long-term memory in adults at risk of Alzheimer’s disease

Claire Lancaster, Ivan Koychev, Jasmine Blane, Amy Chinner, Christopher, Chatham, Kirsten Taylor, Chris Hinds

Journal of Clinical and Experimental Neuropsychology. 2019



Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia

Maria-Eleni Dounavi, Elijah Mak, Katie Wells, Karen Ritchie, Craig W. Ritchie,  Li Su, John T.O’ Brien 

Neurobiology of Ageing. 2020



In this study, we found that participants with an APOEe4 genotype (a known genetic risk factor for dementia) were more likely to have a smaller hippocampal molecular layer, and this change was apparent at both the baseline and 2-year follow up.

Together with previous findings, it appears that the molecular layer may be one of the first areas to show vulnerability to the pathological hallmarks of Alzheimer’s. However, it was noted that differences in the molecular layer were not significantly related to dementia risk defined by family history or cardiovascular factors.

Watch: Meet Our Researchers

In 2019 the PREVENT Dementia Programme held it’s first General Assembly. Hosted by Trinity College Dublin, this meeting provided an opportunity for researchers from across the PREVENT network to gather and exchange ideas on the many different plans for analysis of all areas of the cohort data. Here we meet a number of our PREVENT researchers, discover their roles within the programme and ask how they found the inaugural PREVENT General Assembly.

Sarah Gregory // PhD Student & Study Coordinator // Edinburgh


Dr Riccardo Marioni // Genetics Lead // Edinburgh


Coco Newton // PhD Student // Cambridge


Prof Brian Lawlor // Principal Investigator // Dublin


Prof Alison Wray // Linguistics Lead // Cardiff


Dr Elijah Mak // Postdoctoral Researcher // Cambridge


Prof John O’Brien // Principal Investigator & Imaging Lead // Cambridge


Rob Hilary // PhD Student // Edinburgh


Dr Stephen Carter // Postdoctoral Researcher// Cambridge