Cognition

Protocol for a conversation-based analysis study: PREVENT-ED investigates dialogue features that may help predict dementia onset in later life

Sofia de la Fuente Garcia, Craig W. Ritchie, and Saturnino Luz

BMJ Open. 2019

DOI: 10.1136/bmjopen-2018-026254 

This publication lays out plans for the PREVENT Elicitation of Dialogues (PREVENT-ED) substudy. This project aims to analyse specific features of speech during conversation with PREVENT participants. The researchers seek to determine if there are any associations between changes in spoken dialogue and other risk factors for Alzheimer’s disease. Ultimately they want to know whether such dialogue analysis could be useful in screening for early stages of disease.

Allocentric and Egocentric Spatial Processing in Middle-Aged Adults at High Risk of Late-Onset Alzheimer’s Disease: The PREVENT Dementia Study

Karen Ritchie, Isabelle Carriere, David Howett, Li Su, Michael Hornberger, John T. O’Brien, Craig W. Ritchie and Dennis Chan.
Journal of Alzheimer’s Disease 65 (2018)
10.3233/JAD-180432

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The midlife cognitive profiles of adults at high risk of late-onset Alzheimer’s disease: The PREVENT study.

Ritchie K, Carrière I, Su L, O’Brien JT, Lovestone S, Wells K, Ritchie CW.
Alzheimer’s & dementia: the journal of the Alzheimer’s Association. 2017
10.1016/j.jalz.2017.02.008

Researchers analysed the results from PREVENT participants on various memory and thinking assessments. They found performance on particular spatial and navigation based tasks may be useful in differentiating between those deemed at high or low risk for later life dementia.

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