At, with and beyond risk: expectations of living with the possibility of future dementia.

Milne R, Diaz A, Badger S, Bunnik E, Fauria K, Wells K.
Sociology of health & illness. 2017.

Focus groups were held with PREVENT participants to develop discussions around disclosure of dementia risk.

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Cerebral small vessel disease in middle age and genetic predisposition to late-onset Alzheimer’s disease.

Stefaniak JD, Su L, Mak E, Sheikh-Bahaei N, Wells K, Ritchie K, Waldman A, Ritchie CW, O’Brien JT.
Alzheimer’s & Dementia. 2017

Studying brain scans of PREVENT participants, the health of the small blood vessels that feed the brain did not appear to significantly differ between those considered at higher risk of Alzheimer’s disease based on genetic factors compared to those at lower risk.

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The PREVENT research programme–a novel research programme to identify and manage midlife risk for dementia: the conceptual framework.

Ritchie CW, Wells K, Ritchie K.
International Review of Psychiatry. 2013

This article outlines the vision of the PREVENT study and how, through in depth study of people in their mid-life, PREVENT can generate novel evidence to inform future interventional trials and improve future care.

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The PREVENT study: a prospective cohort study to identify mid-life biomarkers of late-onset Alzheimer’s disease.

Ritchie CW, Ritchie K.

BMJ open. 2012


This publication describes the importance of developing a study to investigate markers present in midlife that could identify people at increased risk for later life dementia.

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