Stefaniak JD, Su L, Mak E, Sheikh-Bahaei N, Wells K, Ritchie K, Waldman A, Ritchie CW, O’Brien JT.
Alzheimer’s & Dementia. 2017
Studying brain scans of PREVENT participants, the health of the small blood vessels that feed the brain did not appear to significantly differ between those considered at higher risk of Alzheimer’s disease based on genetic factors compared to those at lower risk.Read More
The group did not find any overall difference in the condition of the blood vessels between participants designated at increased risk of Alzheimer’s compared to those at lower risk. This might suggest that these brain changes happen closer to the onset of Alzheimer’s symptoms and were not yet present in our younger volunteers – with an average age of 51. The scans only captured one snapshot in time and so the group are keen to look at how the brains of PREVENT participants may change as they attend future follow up visits.
Ritchie CW, Wells K, Ritchie K.
International Review of Psychiatry. 2013
This article outlines the vision of the PREVENT study and how, through in depth study of people in their mid-life, PREVENT can generate novel evidence to inform future interventional trials and improve future care.Read More
The authors provide a detailed breakdown of the main aims of the PREVENT programme and introduce the methods used to collect the wide range of information from volunteers. They speculate how knowledge gained from PREVENT and other similar studies can shape future prevention strategies to delay or halt the progression of Alzheimer’s disease.
Ritchie CW, Ritchie K.
BMJ open. 2012
This publication describes the importance of developing a study to investigate markers present in midlife that could identify people at increased risk for later life dementia.Read More